The emergence and global spread of extended-spectrum or AmpC ?-lactamase Pentair UltraTemp ETi Parts (ESBL/AmpC)-producing Enterobacteriaceae in companion animals have led to the hypothesis that companion animals might be reservoirs for cross-species transmission because of their close contact with humans.However, current knowledge in this field is
O6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies
Abstract Background A novel alkylating agent, temozolomide, has proven efficacious in the treatment of malignant gliomas.However, expression of O6-methylguanine-DNA methyltransferase (MGMT) renders glioma cells USB resistant to the treatment, indicating that identification of mechanisms underlying the gene regulation of MGMT is highly required.Alth